Description
BPC 157
BPC 157 comes in a small sterile container containing 5mg.
BPC157 is also known as the following:
Booly protection compound 157, BPC-15, BPC157, Bpc-157, BPC 15; UNII-8ED8NXK95P
Chemical Structure
Chemical Formula
C62H98N16O22
Molar mass
1419.556 g/mol
Chemical Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Description
Body Protection Compound-157, or BPC 157, is a pentadecapeptide which is 15 amino acids connected by a peptide bond. It’s amino acid sequence is similar to part of the human amino acid sequence which can be found in the body’s gastric juice.
Studies
Clinical studies show BPC 157 improves the healing of wounds, which includes tendon injuries such as a transected Achilles tendon. The study investigated which mechanism it utilizes to accelerate the healing of an injured rat Achilles tendon. Two groups were studied. The first group utilized a solution containing BPC 157, the other group used a placebo lacking the peptide. Each culture was monitored for tendon fibroblasts outgrowths. This indicated signs of regeneration. The outgrowth was significantly increased in the culture containing BPC 157 compared to the placebo culture.
Also, a MTT study showed BPC157 doesn’t affect cellular proliferation within a culture of rat Achilles tendon. However, results did show that it increased the number survival of cells experiencing oxidative stress. Furthermore, the Transwell filter migration study showed that it improved in-vitro fibroblast migration. Moreover, it increased the fibroblast dispersal within culture dishes.
Additionally, studies demonstrated that BPC157 induces F-actin creation in fibroblasts. Similarly, Western blot analysis was able to show the activation and production of FAK proteins and paxillin as well as increased both of their extent without affecting the numbers produced.
BPC157 enhances the in-vitro cellular migration and the ex-vivo growth of fibroblasts derived from mouse/rat tendon explants. BPC157 also raises the likely hood of a cell surviving oxidative stress.
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Shipping
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