PEG MGF (Pegylated Mechano Growth Factor)
PEG MGF is classified as a splice variant of IGF which exists because of a frameshift when the IGF gene is PEGlayted to improve stability. Pegylated Mechano Growth Factor is a variation of IGF produced as a result of a frameshift when the IGF gene, called MGF is PEGylated to improve stability, thereby outperforming the natural MGF. MGF is classified as a splice variant that enables muscle fibers to mature and fuse. Unlike Natural MGF that doesn’t travel in the bloodstream, Synthetic MGF has the ability to move in the bloodstream, although it has a short active life in the bloodstream. Studies show the PEG-MGF can help to increase the muscle stem cell count
What is PEG-MGF
PEGylation is the phenomenon whereby a Polyethylene glycol structure (PEG structure) is attached to a larger molecule such as MGF. The PEG forms a protective layer around the larger molecule to enable it to pass through the bloodstream without any breakdown. Studies show that PEGylated MGF results in a more stable MGF in the bloodstream.
The Effects of PEGlayted MGF
MGF on its own cannot travel through the bloodstream without breaking down. It will require a form of modification if it is to last in the bloodstream and this is where PEGylation comes into play. Natural MGF does not enter the bloodstream, and synthetic MGF only lasts a few minutes in the bloodstream when injected. With PEGYLATION, the MGF is able to travel in the bloodstream without any breakdown. This is because the Polyethylene glycol acts as a protective cover that shields the peptide just enough for it carry out its biological function.
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