Description
S23 SARM 25mg x 30ml
Buy S23 SARM online today at Peptides for Sale. S23 comes in a green 30ml plastic sterile container containing a homogeneous mixture with 25mg per ml of S23 (SARM).
S23 SARM is also known as the following:
S-23, S23, S-23 SARM,
Chemical Structure
S23 SARM Chemical Structure
Chemical Name
(2S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide
Chemical Formula
C18H13ClF4N2O3
Molar mass
416.753 g/mol
Description
S23’s pharmacologic effects were characterized in male rats as a hormonal male contraception. S-23 showed high binding affinity (inhibitory constant = 1.7 +/- 0.2 nm) and was identified as a full agonist in vitro.
In castrated male rats, the ED50 of S-23 in the prostate and levator ani muscle was 0.43 and 0.079 mg/d, respectively whereas in intact male rats treated for 14 d, S-23 alone suppressed LH levels by greater than 50% at doses greater than 0.1 mg/d, with corresponding decreases in the size of the prostate but increases in the size of levator ani muscle.
In intact male rats treated for up to 10 wk with S-23 and estradiol benzoate (EB; necessary to maintain sexual behavior in rats), S-23 showed biphasic effects on androgenic tissues and spermatogenesis by suppressing serum concentrations of LH and FSH. EB alone showed no effect on spermatogenesis. In the EB + S-23 (0.1 mg/d) group, four of six animals showed no sperm in the testis and zero pregnancies (none of six) in mating trials.
Infertility was fully reversible after termination of treatment and had a 100% pregnancy rate observed after a 100-day recovery. S-23 increased bone mineral density and lean mass but reduced fat mass in a dose-dependent manner. This first study shows a selective androgen receptor modulator combined with EB is an effective and reversible regimen for hormonal male contraception in rats. The beneficial effects of S-23 on the muscle, tissue selectivity, and favorable pharmacokinetic properties make it a strong candidate for use in oral male contraception.
Quality Research Chemicals
Peptidesforsale.net prides itself on providing consistent high-quality research chemicals and peptides. Always choose Peptides for Sale to buy S23 or any other SARM or Research Chemical because we deliver high-quality consistent sterile products. Furthermore, we and ship fast from the USA. Peptidesforsale.net is your number one source when you buy research chemical and peptides online.
Shipping
Free shipping on orders over $150 and in addition please remember all orders ship from the USA.
